Protein structure determination in human cells by in-cell NMR and a reporter system to optimize prot...
Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Most experimental methods for structural biology proceed in vitro and therefore the contribution of the intracellular environment on protein structure and dynamics is absent. Studying proteins at atomic resolution in living mammalian cells has been elusive due to the lack of methodologies. In-cell nuclear magnetic resonance spectroscopy (in-cell NM...
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Full title
Protein structure determination in human cells by in-cell NMR and a reporter system to optimize protein delivery or transexpression
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TN_cdi_doaj_primary_oai_doaj_org_article_cd54d82a635a4d768be4cf377bb68830
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd54d82a635a4d768be4cf377bb68830
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-04251-6
