Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induce...
Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain
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Author / Creator
Li, Yu-Jiao , Zhang, Kun , Sun, Ting , Wang, Jian , Guo, Yan-Yan , Yang, Le , Yang, Qi , Li, Yan-Jiao , Liu, Shui-Bing , Zhao, Ming-Gao and Wu, Yu-Mei
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Liver X receptors (LXRs), including LXRα and LXRβ, are key regulators of transcriptional programs for both cholesterol homeostasis and inflammation in the brain. Here, the modes of action of LXRs and the epigenetic mechanisms regulating LXRβ expression in anterior cingulate cortex (ACC) of chronic inflammatory pain (CIP) are investigated.
The de...
Alternative Titles
Full title
Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cd8738eef9e3446caaf20db7674cb135
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd8738eef9e3446caaf20db7674cb135
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1507-3
