Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogene...
Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hepatic steatosis develops when lipid influx and production exceed the liver’s ability to utilize/export triglycerides. Obesity promotes steatosis and is characterized by leptin resistance. A role of leptin in hepatic lipid handling is highlighted by the observation that recombinant leptin reverses steatosis of hypoleptinemic patients with lipodyst...
Alternative Titles
Full title
Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_cd9c6af3dc684233ae9e0068539f7123
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd9c6af3dc684233ae9e0068539f7123
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10684-1
