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NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdbdd2558fdc456aa6bffb6167e61b9a

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

About this item

Full title

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2021-12, Vol.10 (12), p.3514

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

This study investigates the diagnostic and prognostic potential of different forms of tau in biofluids from patients with Creutzfeldt-Jakob disease (CJD). Extracellular tau, which is molecularly heterogeneous, was measured using ultra-sensitive custom-made Simoa assays for N-terminal (NT1), mid-region, and full-length tau. We assessed cross-section...

Alternative Titles

Full title

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cdbdd2558fdc456aa6bffb6167e61b9a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdbdd2558fdc456aa6bffb6167e61b9a

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells10123514

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