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The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex...

The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdc7c5fa64a14a05be684ec9058832ff

The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex with High Accuracy

About this item

Full title

The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex with High Accuracy

Author / Creator

Publisher

Basel: MDPI AG

Journal title

Magnetochemistry, 2018-03, Vol.4 (1), p.12

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Structural characterization of complexes is crucial for a better understanding of biological processes and structure-based drug design. However, many protein–ligand structures are not solvable by X-ray crystallography, for example those with low affinity binders or dynamic binding sites. Such complexes are usually targeted by solution-state NMR spe...

Alternative Titles

Full title

The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex with High Accuracy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cdc7c5fa64a14a05be684ec9058832ff

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cdc7c5fa64a14a05be684ec9058832ff

Other Identifiers

ISSN

2312-7481

E-ISSN

2312-7481

DOI

10.3390/magnetochemistry4010012

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