Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistan...
Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The limited diversity in targets of available antibiotic therapies has put tremendous pressure on the treatment of bacterial pathogens, where numerous resistance mechanisms that counteract their function are becoming increasingly prevalent. Here, we utilize an unconventional anti-virulence screen of host-guest interacting macrocycles, and identify...
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Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii
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TN_cdi_doaj_primary_oai_doaj_org_article_ce32b3bb75ca43ada00bf2e937ef276d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce32b3bb75ca43ada00bf2e937ef276d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37749-6