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Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce4db38e03334ce29e4228c492ac1adb

Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

About this item

Full title

Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2024-06, Vol.12

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

During macroautophagy, cytoplasmic constituents are engulfed by autophagosomes. Lysosomes fuse with closed autophagosomes but not with unclosed intermediate structures. This is achieved in part by the late recruitment of the autophagosomal SNARE syntaxin 17 (STX17) to mature autophagosomes. However, how STX17 recognizes autophagosome maturation is...

Alternative Titles

Full title

Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ce4db38e03334ce29e4228c492ac1adb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ce4db38e03334ce29e4228c492ac1adb

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.92189

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