Genetic regulation of RNA splicing in human pancreatic islets
Genetic regulation of RNA splicing in human pancreatic islets
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Author / Creator
Atla, Goutham , Bonàs-Guarch, Silvia , Cuenca-Ardura, Mirabai , Beucher, Anthony , Crouch, Daniel J. M. , Garcia-Hurtado, Javier , Moran, Ignasi , Cnop, Miriam , Eliasson, Lena , Esguerra, Jonathan Lou S. , Eizirik, Décio L. , Groop, Leif , Jensen, Thomas S. , Hansen, Torben , Marchetti, Piero , Mercader, Josep M. , Mulder, Hindrik , Stabile-Barnett, Chris R. , Thirion, Christian , Torrents, David , Irimia, Manuel , Prasad, Rashmi B. , Gloyn, Anna L. , Marselli, Lorella , Suleiman, Mara , Berney, Thierry , de Koning, Eelco J. P. , Kerr-Conte, Julie , Pattou, Francois , Todd, John A. , Piemonti, Lorenzo , Ferrer, Jorge , the T2DSystems Consortium , T2DSystems Consortium , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Translationell muskelforskning , Diabetes - molekylär metabolism , Institutionen för kliniska vetenskaper, Malmö , Strategic research areas (SRA) , Lunds universitet , Diabetes - öcellsexocytos , Translational Muscle Research , Profilområden och andra starka forskningsmiljöer , Lund University , EXODIAB: Excellence of Diabetes Research in Sweden , Diabetes - Islet Cell Exocytosis , Profile areas and other strong research environments , Department of Clinical Sciences, Malmö and Diabetes - Molecular Metabolism
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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More information
Scope and Contents
Contents
Non-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk. For many loci, however, the mechanisms through which non-coding variants influence diabetes susceptibility are unknown.
We examine splicing...
Alternative Titles
Full title
Genetic regulation of RNA splicing in human pancreatic islets
Authors, Artists and Contributors
Author / Creator
Bonàs-Guarch, Silvia
Cuenca-Ardura, Mirabai
Beucher, Anthony
Crouch, Daniel J. M.
Garcia-Hurtado, Javier
Moran, Ignasi
Cnop, Miriam
Eliasson, Lena
Esguerra, Jonathan Lou S.
Eizirik, Décio L.
Groop, Leif
Jensen, Thomas S.
Hansen, Torben
Marchetti, Piero
Mercader, Josep M.
Mulder, Hindrik
Stabile-Barnett, Chris R.
Thirion, Christian
Torrents, David
Irimia, Manuel
Prasad, Rashmi B.
Gloyn, Anna L.
Marselli, Lorella
Suleiman, Mara
Berney, Thierry
de Koning, Eelco J. P.
Kerr-Conte, Julie
Pattou, Francois
Todd, John A.
Piemonti, Lorenzo
Ferrer, Jorge
the T2DSystems Consortium
T2DSystems Consortium
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Translationell muskelforskning
Diabetes - molekylär metabolism
Institutionen för kliniska vetenskaper, Malmö
Strategic research areas (SRA)
Lunds universitet
Diabetes - öcellsexocytos
Translational Muscle Research
Profilområden och andra starka forskningsmiljöer
Lund University
EXODIAB: Excellence of Diabetes Research in Sweden
Diabetes - Islet Cell Exocytosis
Profile areas and other strong research environments
Department of Clinical Sciences, Malmö
Diabetes - Molecular Metabolism
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cf1281e02aac42cea7c15b4711ce5611
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cf1281e02aac42cea7c15b4711ce5611
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-022-02757-0
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