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ArticlesPeer ReviewedFull Text
Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals
Author / Creator:Martín, Guiomar ; Márquez, Yamile ; Mantica, Federica ; Duque, Paula ; Irimia, Manuel
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2021-01, Vol.22 (1), p.35-35, Article 35
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Unique transcriptomes of sensory and non-sensory neurons: insights from Splicing Regulatory States
Author / Creator:Ciampi, Ludovica ; Serrano, Luis ; Irimia, Manuel
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2024-04, Vol.20 (4), p.296-310
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Day-night and seasonal variation of human gene expression across tissues
Author / Creator:Wucher, Valentin ; Sodaei, Reza ; Amador, Raziel ; Irimia, Manuel ; Guigó, Roderic
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2023-02, Vol.21 (2), p.e3001986
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Retention of paternal DNA methylome in the developing zebrafish germline
Author / Creator:Skvortsova, Ksenia ; Tarbashevich, Katsiaryna ; Stehling, Martin ; Lister, Ryan ; Irimia, Manuel ; Raz, Erez ; Bogdanovic, Ozren
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3054-13, Article 3054
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Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings
Author / Creator:Almudi, Isabel ; Vizueta, Joel ; Wyatt, Christopher D. R. ; de Mendoza, Alex ; Marlétaz, Ferdinand ; Firbas, Panos N. ; Feuda, Roberto ; Masiero, Giulio ; Medina, Patricia ; Alcaina-Caro, Ana ; Cruz, Fernando ; Gómez-Garrido, Jessica ; Gut, Marta ; Alioto, Tyler S. ; Vargas-Chavez, Carlos ; Davie, Kristofer ; Misof, Bernhard ; González, Josefa ; Aerts, Stein ; Lister, Ryan ; Paps, Jordi ; Rozas, Julio ; Sánchez-Gracia, Alejandro ; Irimia, Manuel ; Maeso, Ignacio ; Casares, Fernando
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2631-11, Article 2631
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The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
Author / Creator:Barbosa-Morais, Nuno L. ; Irimia, Manuel ; Pan, Qun ; Xiong, Hui Y. ; Gueroussov, Serge ; Lee, Leo J. ; Slobodeniuc, Valentina ; Kutter, Claudia ; Watt, Stephen ; Çolak, Recep ; Kim, TaeHyung ; Misquitta-Ali, Christine M. ; Wilson, Michael D. ; Kim, Philip M. ; Odom, Duncan T. ; Frey, Brendan J. ; Blencowe, Benjamin J.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-12, Vol.338 (6114), p.1587-1593
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Regulated aggregative multicellularity in a close unicellular relative of metazoa
Author / Creator:Sebé-Pedrós, Arnau ; Irimia, Manuel ; del Campo, Javier ; Parra-Acero, Helena ; Russ, Carsten ; Nusbaum, Chad ; Blencowe, Benjamin J ; Ruiz-Trillo, Iñaki
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2013-12, Vol.2, p.e01287
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Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture
Author / Creator:Grau-Bové, Xavier ; Ruiz-Trillo, Iñaki ; Irimia, Manuel
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2018-09, Vol.19 (1), p.135-135, Article 135
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An alternative splicing event amplifies evolutionary differences between vertebrates
Author / Creator:Gueroussov, Serge ; Gonatopoulos-Pournatzis, Thomas ; Irimia, Manuel ; Raj, Bushra ; Lin, Zhen-Yuan ; Gingras, Anne-Claude ; Blencowe, Benjamin J.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-08, Vol.349 (6250), p.868-873
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ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics
Author / Creator:García-Castro, Helena ; Kenny, Nathan J. ; Iglesias, Marta ; Álvarez-Campos, Patricia ; Mason, Vincent ; Elek, Anamaria ; Schönauer, Anna ; Sleight, Victoria A. ; Neiro, Jakke ; Aboobaker, Aziz ; Permanyer, Jon ; Irimia, Manuel ; Sebé-Pedrós, Arnau ; Solana, Jordi
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2021-04, Vol.22 (1), p.89-89, Article 89
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Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP
Author / Creator:Vigevani, Luisa ; Gohr, André ; Webb, Thomas ; Irimia, Manuel ; Valcárcel, Juan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.2100-15, Article 2100
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ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Author / Creator:Márquez, Yamile ; Mantica, Federica ; Cozzuto, Luca ; Burguera, Demian ; Hermoso-Pulido, Antonio ; Ponomarenko, Julia ; Roy, Scott W. ; Irimia, Manuel
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2021-08, Vol.22 (1), p.239-239, Article 239
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Drosophila ovarian stem cell niche ageing involves coordinated changes in transcription and alternative splicing
Author / Creator:Even-Ros, Dilamm ; Huertas-Romero, Judit ; Marín-Menguiano, Miriam ; Nusspaumer, Gretel ; Borge, Miguel ; Irimia, Manuel ; Zurita, Federico ; González-Reyes, Acaimo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2596-17, Article 2596
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The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians
Author / Creator:Spruce, Thomas ; Plass, Mireya ; Gohr, André ; Ray, Debashish ; Martínez de Lagrán, María ; Rot, Gregor ; Nóvoa, Ana ; Burguera, Demian ; Permanyer, Jon ; Miret, Marta ; Zheng, Hong ; Swanson, Maurice S. ; Morris, Quaid ; Mallo, Moises ; Dierssen, Mara ; Hughes, Timothy R. ; Pernaute, Barbara ; Irimia, Manuel
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2022-04, Vol.20 (4), p.e3001615
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5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
Author / Creator:Khare, Tarang ; Pai, Shraddha ; Koncevicius, Karolis ; Pal, Mrinal ; Kriukiene, Edita ; Liutkeviciute, Zita ; Irimia, Manuel ; Jia, Peixin ; Ptak, Carolyn ; Xia, Menghang ; Tice, Raymond ; Tochigi, Mamoru ; Moréra, Solange ; Nazarians, Anaies ; Belsham, Denise ; Wong, Albert H C ; Blencowe, Benjamin J ; Wang, Sun Chong ; Kapranov, Philipp ; Kustra, Rafal ; Labrie, Viviane ; Klimasauskas, Saulius ; Petronis, Arturas
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2012-10, Vol.19 (10), p.1037-1043
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Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain
Author / Creator:Albuixech-Crespo, Beatriz ; López-Blanch, Laura ; Burguera, Demian ; Maeso, Ignacio ; Sánchez-Arrones, Luisa ; Moreno-Bravo, Juan Antonio ; Somorjai, Ildiko ; Pascual-Anaya, Juan ; Puelles, Eduardo ; Bovolenta, Paola ; Garcia-Fernàndez, Jordi ; Puelles, Luis ; Irimia, Manuel ; Ferran, José Luis
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-04, Vol.15 (4), p.e2001573
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An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm
Author / Creator:Grau-Bové, Xavier ; Subirana, Lucie ; Meister, Lydvina ; Soubigou, Anaël ; Neto, Ana ; Elek, Anamaria ; Naranjo, Silvia ; Fornas, Oscar ; Gomez-Skarmeta, Jose Luis ; Tena, Juan J. ; Irimia, Manuel ; Bertrand, Stéphanie ; Sebé-Pedrós, Arnau ; Escriva, Hector
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-05, Vol.15 (1), p.4550-18, Article 4550
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Parallel evolution of amphioxus and vertebrate small-scale gene duplications
Author / Creator:Brasó-Vives, Marina ; Marlétaz, Ferdinand ; Echchiki, Amina ; Mantica, Federica ; Acemel, Rafael D. ; Gómez-Skarmeta, José L. ; Hartasánchez, Diego A. ; Le Targa, Lorlane ; Pontarotti, Pierre ; Tena, Juan J. ; Maeso, Ignacio ; Escriva, Hector ; Irimia, Manuel ; Robinson-Rechavi, Marc
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2022-11, Vol.23 (1), p.243-243, Article 243
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Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals
Author / Creator:de Mendoza, Alex ; Suga, Hiroshi ; Permanyer, Jon ; Irimia, Manuel ; Ruiz-Trillo, Iñaki
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2015-10, Vol.4, p.e08904-e08904
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Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers
Author / Creator:Head, Sarah A. ; Hernandez-Alias, Xavier ; Yang, Jae-Seong ; Ciampi, Ludovica ; Beltran-Sastre, Violeta ; Torres-Méndez, Antonio ; Irimia, Manuel ; Schaefer, Martin H. ; Serrano, Luis
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2021-02, Vol.19 (2), p.e3001138
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Showing 1 to 20 of 132 results

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Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals

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Unique transcriptomes of sensory and non-sensory neurons: insights from Splicing Regulatory States

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Day-night and seasonal variation of human gene expression across tissues

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Retention of paternal DNA methylome in the developing zebrafish germline

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Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings

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The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

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Regulated aggregative multicellularity in a close unicellular relative of metazoa

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Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture

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An alternative splicing event amplifies evolutionary differences between vertebrates

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ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics

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Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP

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ExOrthist: a tool to infer exon orthologies at any evolutionary distance

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Drosophila ovarian stem cell niche ageing involves coordinated changes in transcription and alternative splicing

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The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians

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5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary

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Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain

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An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm

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Parallel evolution of amphioxus and vertebrate small-scale gene duplications

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Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals

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Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers

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