Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons
Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons
About this item
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Author / Creator
Liu, Yanan , Hu, Longmiao , Wu, Zhengzhen , Yuan, Kun , Hong, Guangliang , Lian, Zhengke , Feng, Juanjuan , Li, Na , Li, Dali , Wong, Jiemin , Chen, Jiekai , Liu, Mingyao , He, Jiangping and Pang, Xiufeng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Immunotherapy has become established as major treatment modality for multiple types of solid tumors, including colorectal cancer. Identifying novel immunotherapeutic targets to enhance anti-tumor immunity and sensitize current immune checkpoint blockade (ICB) in colorectal cancer is needed. Here we report the histone demethylase PHD finger protein...
Alternative Titles
Full title
Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons
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TN_cdi_doaj_primary_oai_doaj_org_article_cfd906eb22b048cdb7a03488a79f3fcd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cfd906eb22b048cdb7a03488a79f3fcd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39943-y
