Prediction of combination therapies based on topological modeling of the immune signaling network in...
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
About this item
Full title
Author / Creator
Bernardo-Faura, Marti , Rinas, Melanie , Wirbel, Jakob , Pertsovskaya, Inna , Pliaka, Vicky , Messinis, Dimitris E , Vila, Gemma , Sakellaropoulos, Theodore , Faigle, Wolfgang , Stridh, Pernilla , Behrens, Janina R , Olsson, Tomas , Martin, Roland , Paul, Friedemann , Alexopoulos, Leonidas G , Villoslada, Pablo and Saez-Rodriguez, Julio
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may produce severe side effects.
Here, we applied a network-ba...
Alternative Titles
Full title
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis
Authors, Artists and Contributors
Author / Creator
Rinas, Melanie
Wirbel, Jakob
Pertsovskaya, Inna
Pliaka, Vicky
Messinis, Dimitris E
Vila, Gemma
Sakellaropoulos, Theodore
Faigle, Wolfgang
Stridh, Pernilla
Behrens, Janina R
Olsson, Tomas
Martin, Roland
Paul, Friedemann
Alexopoulos, Leonidas G
Villoslada, Pablo
Saez-Rodriguez, Julio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d0283f3687a1440293ae0739ffafff56
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0283f3687a1440293ae0739ffafff56
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-021-00925-8
