Peptide fusion improves prime editing efficiency
Peptide fusion improves prime editing efficiency
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Prime editing enables search-and-replace genome editing but is limited by low editing efficiency. We present a high-throughput approach, the Peptide Self-Editing sequencing assay (PepSEq), to measure how fusion of 12,000 85-amino acid peptides influences prime editing efficiency. We show that peptide fusion can enhance prime editing, prime-enhancin...
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Peptide fusion improves prime editing efficiency
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TN_cdi_doaj_primary_oai_doaj_org_article_d055f5b29f2642d4ace3d63f203574ad
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d055f5b29f2642d4ace3d63f203574ad
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31270-y
