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Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lin...

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d088ebf1f5634ab2825caf74af90cb4a

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

About this item

Full title

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2021-04, Vol.21 (1), p.481-481, Article 481

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

One key approach for anticancer therapy is drug combination. Drug combinations can help reduce doses and thereby decrease side effects. Furthermore, the likelihood of drug resistance is reduced. Distinct alterations in tumor metabolism have been described in past decades, but metabolism has yet to be targeted in clinical cancer therapy. Recently, w...

Alternative Titles

Full title

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d088ebf1f5634ab2825caf74af90cb4a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d088ebf1f5634ab2825caf74af90cb4a

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-021-08186-9

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