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Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disea...

Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c5ed539cee41988dd42e2b43cc0c3f

Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk

About this item

Full title

Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk

Publisher

England: BioMed Central Ltd

Journal title

BMC research notes, 2011-09, Vol.4 (1), p.327-327, Article 327

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Tau abnormal hyperphosphorylation and the formation of neurofibrillary tangles in AD brain is the result of upregulation of tau kinases and downregulation of tau phosphatases.
In a group of 729 Spanish late-onset Alzheimer's disease (AD) patients and 670 healthy controls, we examined variations into a set of candidate genes (PPP2CA, PPP2R2A, ANP...

Alternative Titles

Full title

Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d0c5ed539cee41988dd42e2b43cc0c3f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0c5ed539cee41988dd42e2b43cc0c3f

Other Identifiers

ISSN

1756-0500

E-ISSN

1756-0500

DOI

10.1186/1756-0500-4-327

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