Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
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England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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The Polycomb repressive complex 2 (PRC2) is a multicomponent histone H3K27 methyltransferase complex, best known for silencing the
genes during embryonic development. The Polycomb-like proteins PHF1, MTF2, and PHF19 are critical components of PRC2 by stimulating its catalytic activity in embryonic stem cells. The Tudor domains of PHF1/19 have be...
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Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
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TN_cdi_doaj_primary_oai_doaj_org_article_d0f739c51f80453785f7998782534307
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d0f739c51f80453785f7998782534307
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.58675
