Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarci...
Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma
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Author / Creator
Song, Guohe , Shi, Yang , Meng, Lu , Ma, Jiaqiang , Huang, Siyuan , Zhang, Juan , Wu, Yingcheng , Li, Jiaxin , Lin, Youpei , Yang, Shuaixi , Rao, Dongning , Cheng, Yifei , Lin, Jian , Ji, Shuyi , Liu, Yuming , Jiang, Shan , Wang, Xiaoliang , Zhang, Shu , Ke, Aiwu , Wang, Xiaoying , Cao, Ya , Ji, Yuan , Zhou, Jian , Fan, Jia , Zhang, Xiaoming , Xi, Ruibin and Gao, Qiang
Publisher
England: Nature Portfolio
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English
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Publisher
England: Nature Portfolio
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Contents
Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by performing single-cell RNA sequencing on 144,878 cells from 14 pairs of iCCA tumors and non-tumor liver tissues, we find that S100P and SPP1 are two markers for iCCA perihilar large duct type...
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Full title
Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma
Authors, Artists and Contributors
Author / Creator
Shi, Yang
Meng, Lu
Ma, Jiaqiang
Huang, Siyuan
Zhang, Juan
Wu, Yingcheng
Li, Jiaxin
Lin, Youpei
Yang, Shuaixi
Rao, Dongning
Cheng, Yifei
Lin, Jian
Ji, Shuyi
Liu, Yuming
Jiang, Shan
Wang, Xiaoliang
Zhang, Shu
Ke, Aiwu
Wang, Xiaoying
Cao, Ya
Ji, Yuan
Zhou, Jian
Fan, Jia
Zhang, Xiaoming
Xi, Ruibin
Gao, Qiang
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TN_cdi_doaj_primary_oai_doaj_org_article_d1872e649e1344dba5a7cc26ee3c1275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1872e649e1344dba5a7cc26ee3c1275
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E-ISSN
2041-1723
DOI
10.1038/s41467-022-29164-0