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Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarci...

Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarci...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1872e649e1344dba5a7cc26ee3c1275

Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma

About this item

Full title

Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma

Publisher

England: Nature Portfolio

Journal title

Nature communications, 2022-03, Vol.13 (1), p.1642-1642

Language

English

Formats

Publication information

Publisher

England: Nature Portfolio

More information

Scope and Contents

Contents

Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by performing single-cell RNA sequencing on 144,878 cells from 14 pairs of iCCA tumors and non-tumor liver tissues, we find that S100P and SPP1 are two markers for iCCA perihilar large duct type...

Alternative Titles

Full title

Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d1872e649e1344dba5a7cc26ee3c1275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1872e649e1344dba5a7cc26ee3c1275

Other Identifiers

E-ISSN

2041-1723

DOI

10.1038/s41467-022-29164-0

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