Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in...
Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer’s disease
About this item
Full title
Author / Creator
Sanchez-Rodriguez, Lazaro M. , Bezgin, Gleb , Carbonell, Felix , Therriault, Joseph , Fernandez-Arias, Jaime , Servaes, Stijn , Rahmouni, Nesrine , Tissot, Cécile , Stevenson, Jenna , Karikari, Thomas K. , Ashton, Nicholas J. , Benedet, Andréa L. , Zetterberg, Henrik , Blennow, Kaj , Triana-Baltzer, Gallen , Kolb, Hartmuth C. , Rosa-Neto, Pedro , Iturria-Medina, Yasser and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neuronal dysfunction and cognitive deterioration in Alzheimer’s disease (AD) are likely caused by multiple pathophysiological factors. However, mechanistic evidence in humans remains scarce, requiring improved non-invasive techniques and integrative models. We introduce personalized AD computational models built on whole-brain Wilson-Cowan oscillat...
Alternative Titles
Full title
Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Bezgin, Gleb
Carbonell, Felix
Therriault, Joseph
Fernandez-Arias, Jaime
Servaes, Stijn
Rahmouni, Nesrine
Tissot, Cécile
Stevenson, Jenna
Karikari, Thomas K.
Ashton, Nicholas J.
Benedet, Andréa L.
Zetterberg, Henrik
Blennow, Kaj
Triana-Baltzer, Gallen
Kolb, Hartmuth C.
Rosa-Neto, Pedro
Iturria-Medina, Yasser
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d1d394702b194a57a434755661c25a8f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d1d394702b194a57a434755661c25a8f
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-06217-2
