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A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d237beec5d754883864eedecfd2f71be

A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

About this item

Full title

A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-11, Vol.9 (1), p.5012-11, Article 5012

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although polymerase chain reaction (PCR) is the most widely used method for DNA amplification, the requirement of thermocycling limits its non-laboratory applications. Isothermal DNA amplification techniques are hence valuable for on-site diagnostic applications in place of traditional PCR. Here we describe a true isothermal approach for amplifying...

Alternative Titles

Full title

A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d237beec5d754883864eedecfd2f71be

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d237beec5d754883864eedecfd2f71be

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-07324-5

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