Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live muri...
Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Monoclonal antibodies (abs) targeting the programmed cell death 1 (PD-1) immune checkpoint pathway have revolutionized tumor therapy. Because T-cell-directed PD-1 blockade boosts tumor immunity, anti-PD-1 abs have been developed for examining T-cell-PD-1 functions. More recently, PD-1 expression has also been reported directly on cancer cells of va...
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Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_d2e344242cfd4990a98e6ad3d7dce9a7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d2e344242cfd4990a98e6ad3d7dce9a7
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-16776-1
