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Genetic modification of primary human B cells to model high-grade lymphoma

Genetic modification of primary human B cells to model high-grade lymphoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d3c9bc11a5cc4cb39c1c847ddd0e75b2

Genetic modification of primary human B cells to model high-grade lymphoma

About this item

Full title

Genetic modification of primary human B cells to model high-grade lymphoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-10, Vol.10 (1), p.4543-16, Article 4543

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sequencing studies of diffuse large B cell lymphoma (DLBCL) have identified hundreds of recurrently altered genes. However, it remains largely unknown whether and how these mutations may contribute to lymphomagenesis, either individually or in combination. Existing strategies to address this problem predominantly utilize cell lines, which are limit...

Alternative Titles

Full title

Genetic modification of primary human B cells to model high-grade lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d3c9bc11a5cc4cb39c1c847ddd0e75b2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d3c9bc11a5cc4cb39c1c847ddd0e75b2

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12494-x

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