Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly...
Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion
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Author / Creator
Wang, Wenbiao , Li, Geng , De Wu , Luo, Zhen , Pan, Pan , Tian, Mingfu , Wang, Yingchong , Xiao, Feng , Li, Aixin , Wu, Kailang , Liu, Xiaohong , Rao, Lang , Liu, Fang , Liu, Yingle and Wu, Jianguo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays a key role in host innate immune responses by activating caspase-1 to facilitate interleukin-1β (IL-1β) secretion. Here we report that ZIKV stimulates IL-1β secretion in infected patients, h...
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Full title
Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d3ea3c77bb8f47dd80e55a66920d4519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d3ea3c77bb8f47dd80e55a66920d4519
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02645-3
