METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6...
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner
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Author / Creator
Han, Jie , Wang, Jing-Zi , Yang, Xiao , Yu, Hao , Zhou, Rui , Lu, Hong-Cheng , Yuan, Wen-Bo , Lu, Jian-Chen , Zhou, Zi-Jian , Lu, Qiang , Wei, Ji-Fu and Yang, Haiwei
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
METTL3 is known to be involved in all stages in the life cycle of RNA. It affects the tumor formation by the regulation the m6A modification in the mRNAs of critical oncogenes or tumor suppressors. In bladder cancer, METTL3 could promote the bladder cancer progression via AFF4/NF-κB/MYC signaling network by an m6A dependent manner. Recently, METTL3...
Alternative Titles
Full title
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d4379edee3674d00a486a94f2295b613
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d4379edee3674d00a486a94f2295b613
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-019-1036-9
