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Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament funct...

Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament funct...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d49c4a80c40642788272abc5c212eb04

Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function

About this item

Full title

Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-09, Vol.12 (1), p.5545-5545, Article 5545

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The RAD51 recombinase assembles as helical nucleoprotein filaments on single-stranded DNA (ssDNA) and mediates invasion and strand exchange with homologous duplex DNA (dsDNA) during homologous recombination (HR), as well as protection and restart of stalled replication forks. Strand invasion by RAD51-ssDNA complexes depends on ATP binding. However,...

Alternative Titles

Full title

Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d49c4a80c40642788272abc5c212eb04

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d49c4a80c40642788272abc5c212eb04

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25830-x

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