Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggeri...
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity
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Author / Creator
Ni, Zhexin , Li, Yangshuo , Song, Di , Ding, Jie , Mei, Shanshan , Sun, Shuai , Cheng, Wen , Yu, Jin , Zhou, Ling , Kuang, Yanping , Li, Mingqing , Cai, Zailong and Yu, Chaoqin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Endometriosis (EMs) occurs in approximately 50% of women with infertility. The main causes of EMs-related infertility are follicle dysplasia and reduced oocyte quality. Iron overload occurs in ovarian follicular fluid (FF) of patients with EMs, and this condition is associated with oocyte maturation disorder. However, the underlying molecular mecha...
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Full title
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity
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TN_cdi_doaj_primary_oai_doaj_org_article_d529eff527c941ac812bd6df91c03783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d529eff527c941ac812bd6df91c03783
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05037-8
