Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
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Author / Creator
Mallm, Jan‐Philipp , Iskar, Murat , Ishaque, Naveed , Klett, Lara C , Kugler, Sabrina J , Muino, Jose M , Teif, Vladimir B , Poos, Alexandra M , Großmann, Sebastian , Erdel, Fabian , Tavernari, Daniele , Koser, Sandra D , Schumacher, Sabrina , Brors, Benedikt , König, Rainer , Remondini, Daniel , Vingron, Martin , Stilgenbauer, Stephan , Lichter, Peter , Zapatka, Marc , Mertens, Daniel and Rippe, Karsten
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In chronic lymphocytic leukemia (CLL), a diverse set of genetic mutations is embedded in a deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of aberrant chromatin features, we mapped DNA methylation, seven histone modifications, nucleosome positions, chromatin accessibility, binding of EBF1 and CTCF, as well as the...
Alternative Titles
Full title
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Authors, Artists and Contributors
Author / Creator
Iskar, Murat
Ishaque, Naveed
Klett, Lara C
Kugler, Sabrina J
Muino, Jose M
Teif, Vladimir B
Poos, Alexandra M
Großmann, Sebastian
Erdel, Fabian
Tavernari, Daniele
Koser, Sandra D
Schumacher, Sabrina
Brors, Benedikt
König, Rainer
Remondini, Daniel
Vingron, Martin
Stilgenbauer, Stephan
Lichter, Peter
Zapatka, Marc
Mertens, Daniel
Rippe, Karsten
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d531e1d3965044bc9b7dc0b0a7049c9a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d531e1d3965044bc9b7dc0b0a7049c9a
Other Identifiers
ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20188339