The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
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Author / Creator
Zhuang, Xiaodong , Magri, Andrea , Hill, Michelle , Lai, Alvina G. , Kumar, Abhinav , Rambhatla, Srinivasa Bhargav , Donald, Claire L. , Lopez-Clavijo, Andrea F. , Rudge, Simon , Pinnick, Katherine , Chang, Wai Hoong , Wing, Peter A. C. , Brown, Ryan , Qin, Ximing , Simmonds, Peter , Baumert, Thomas F. , Ray, David , Loudon, Andrew , Balfe, Peter , Wakelam, Michael , Butterworth, Sam , Kohl, Alain , Jopling, Catherine L. , Zitzmann, Nicole and McKeating, Jane A.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The circadian clock regulates immune responses to microbes and affects pathogen replication, but the underlying molecular mechanisms are not well understood. Here we demonstrate that the circadian components BMAL1 and REV-ERBα influence several steps in the hepatitis C virus (HCV) life cycle, including particle entry into hepatocytes and RNA genome...
Alternative Titles
Full title
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
Authors, Artists and Contributors
Author / Creator
Magri, Andrea
Hill, Michelle
Lai, Alvina G.
Kumar, Abhinav
Rambhatla, Srinivasa Bhargav
Donald, Claire L.
Lopez-Clavijo, Andrea F.
Rudge, Simon
Pinnick, Katherine
Chang, Wai Hoong
Wing, Peter A. C.
Brown, Ryan
Qin, Ximing
Simmonds, Peter
Baumert, Thomas F.
Ray, David
Loudon, Andrew
Balfe, Peter
Wakelam, Michael
Butterworth, Sam
Kohl, Alain
Jopling, Catherine L.
Zitzmann, Nicole
McKeating, Jane A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d57b7a19acc942b6a61940c29a11b307
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d57b7a19acc942b6a61940c29a11b307
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-08299-7
