Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients w...
Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): study protocol for a phase III randomized controlled trial
About this item
Full title
Author / Creator
Maitre, Thomas , Bonnet, Maryline , Calmy, Alexandra , Raberahona, Mihaja , Rakotoarivelo, Rivonirina Andry , Rakotosamimanana, Niaina , Ambrosioni, Juan , Miró, José M , Debeaudrap, Pierre , Muzoora, Conrad , Davis, Angharad , Meintjes, Graeme , Wasserman, Sean , Wilkinson, Robert , Eholié, Serge , Nogbou, Frédéric Ello , Calvo-Cortes, Maria-Camilla , Chazallon, Corine , Machault, Vanessa , Anglaret, Xavier and Bonnet, Fabrice
Publisher
London: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Background Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB), particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40% in HIV-negative patients and up to 70% in HIV-co-infected patients. To reduce TBM-induced morbidity and mortality, the INTENSE-TBM trial...
Alternative Titles
Full title
Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): study protocol for a phase III randomized controlled trial
Authors, Artists and Contributors
Author / Creator
Bonnet, Maryline
Calmy, Alexandra
Raberahona, Mihaja
Rakotoarivelo, Rivonirina Andry
Rakotosamimanana, Niaina
Ambrosioni, Juan
Miró, José M
Debeaudrap, Pierre
Muzoora, Conrad
Davis, Angharad
Meintjes, Graeme
Wasserman, Sean
Wilkinson, Robert
Eholié, Serge
Nogbou, Frédéric Ello
Calvo-Cortes, Maria-Camilla
Chazallon, Corine
Machault, Vanessa
Anglaret, Xavier
Bonnet, Fabrice
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d5d86ff83f52483e8824561dd054f87f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d5d86ff83f52483e8824561dd054f87f
Other Identifiers
ISSN
1745-6215
E-ISSN
1745-6215
DOI
10.1186/s13063-022-06772-1
