Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase
Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase
About this item
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Author / Creator
Kouba, Tomáš , Koval’, Tomáš , Sudzinová, Petra , Pospíšil, Jiří , Brezovská, Barbora , Hnilicová, Jarmila , Šanderová, Hana , Janoušková, Martina , Šiková, Michaela , Halada, Petr , Sýkora, Michal , Barvík, Ivan , Nováček, Jiří , Trundová, Mária , Dušková, Jarmila , Skálová, Tereza , Chon, URee , Murakami, Katsuhiko S. , Dohnálek, Jan and Krásný, Libor
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
RNA synthesis is central to life, and RNA polymerase (RNAP) depends on accessory factors for recovery from stalled states and adaptation to environmental changes. Here, we investigated the mechanism by which a helicase-like factor HelD recycles RNAP. We report a cryo-EM structure of a complex between the
Mycobacterium smegmatis
RNAP and HelD....
Alternative Titles
Full title
Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase
Authors, Artists and Contributors
Author / Creator
Koval’, Tomáš
Sudzinová, Petra
Pospíšil, Jiří
Brezovská, Barbora
Hnilicová, Jarmila
Šanderová, Hana
Janoušková, Martina
Šiková, Michaela
Halada, Petr
Sýkora, Michal
Barvík, Ivan
Nováček, Jiří
Trundová, Mária
Dušková, Jarmila
Skálová, Tereza
Chon, URee
Murakami, Katsuhiko S.
Dohnálek, Jan
Krásný, Libor
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d65a4f9aaa6b499b97c7834c0fbc8302
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d65a4f9aaa6b499b97c7834c0fbc8302
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20158-4
