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ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d7329f06ba3b4892a2f5791afd48223e

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

About this item

Full title

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-10, Vol.11 (1), p.5226-5226, Article 5226

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Signs of proteostasis failure often entwine with those of metabolic stress at the cellular level. Here, we study protein sequestration during glucose deprivation-induced ATP decline in
Saccharomyces cerevisiae
. Using live-cell imaging, we find that sequestration of misfolded proteins and nascent polypeptides into two distinct compartments, s...

Alternative Titles

Full title

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d7329f06ba3b4892a2f5791afd48223e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d7329f06ba3b4892a2f5791afd48223e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-19104-1

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