Age-associated changes in lineage composition of the enteric nervous system regulate gut health and...
Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease
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Author / Creator
Kulkarni, Subhash , Saha, Monalee , Slosberg, Jared , Singh, Alpana , Nagaraj, Sushma , Becker, Laren , Zhang, Chengxiu , Bukowski, Alicia , Wang, Zhuolun , Liu, Guosheng , Leser, Jenna M , Kumar, Mithra , Bakhshi, Shriya , Anderson, Matthew J , Lewandoski, Mark , Vincent, Elizabeth , Goff, Loyal A and Pasricha, Pankaj Jay
Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The enteric nervous system (ENS), a collection of neural cells contained in the wall of the gut, is of fundamental importance to gastrointestinal and systemic health. According to the prevailing paradigm, the ENS arises from progenitor cells migrating from the neural crest and remains largely unchanged thereafter. Here, we show that the lineage com...
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Full title
Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease
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TN_cdi_doaj_primary_oai_doaj_org_article_d74ff71d09fa45de82dc220b51c19e93
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d74ff71d09fa45de82dc220b51c19e93
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.88051