Log in to save to my catalogue

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious conseque...

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious conseque...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d759dc1317e74a1d8ee0477da93dd162

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus

About this item

Full title

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-04, Vol.13 (1), p.5651-14, Article 5651

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Generalized status epilepticus (SE) triggers a robust neuroinflammatory response involving reactive astrocytosis, activation of brain-resident microglia, and brain infiltration of CCR2+ monocytes. Multiple lines of evidence indicate that quenching SE-induced neuroinflammation can alleviate the adverse consequences of SE, including neuronal damage a...

Alternative Titles

Full title

Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d759dc1317e74a1d8ee0477da93dd162

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d759dc1317e74a1d8ee0477da93dd162

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-32752-9

How to access this item