Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of...
Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Author / Creator
Al-Sabri, Mohamed H , Behare, Neha , Alsehli, Ahmed M , Berkins, Samuel , Arora, Aadeya , Antoniou, Eirini , Moysiadou, Eleni I , Anantha-Krishnan, Sowmya , Cosmen, Patricia D , Vikner, Johanna , Moulin, Thiago C , Ammar, Nourhene , Boukhatmi, Hadi , Clemensson, Laura E , Rask-Andersen, Mathias , Mwinyi, Jessica , Williams, Michael J , Fredriksson, Robert and Schiöth, Helgi B
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The underlying mechanisms for statin-induced myopathy (SIM) are still equivocal. In this study, we employ
to dissect possible underlying mechanisms for SIM. We observe that chronic fluvastatin treatment causes reduced general locomotion activity and climbing ability. In addition, transmission microscopy of dissected skeletal muscles of fluvastat...
Alternative Titles
Full title
Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
Authors, Artists and Contributors
Author / Creator
Behare, Neha
Alsehli, Ahmed M
Berkins, Samuel
Arora, Aadeya
Antoniou, Eirini
Moysiadou, Eleni I
Anantha-Krishnan, Sowmya
Cosmen, Patricia D
Vikner, Johanna
Moulin, Thiago C
Ammar, Nourhene
Boukhatmi, Hadi
Clemensson, Laura E
Rask-Andersen, Mathias
Mwinyi, Jessica
Williams, Michael J
Fredriksson, Robert
Schiöth, Helgi B
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d87b7b6fdc5541df9494759d713adeac
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d87b7b6fdc5541df9494759d713adeac
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11223528
