Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis
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Author / Creator
Wang, Lihua , Wang, Ergang , Prado Balcazar, Jorge , Wu, Zhenzhen , Xiang, Kun , Wang, Yi , Huang, Qiang , Negrete, Marcos , Chen, Kai‐Yuan , Li, Wei , Fu, Yujie , Dohlman, Anders , Mines, Robert , Zhang, Liwen , Kobayashi, Yoshihiko , Chen, Tianyi , Shi, Guizhi , Shen, John Paul , Kopetz, Scott , Tata, Purushothama Rao , Moreno, Victor , Gersbach, Charles , Crawford, Gregory , Hsu, David , Huang, Emina , Bu, Pengcheng and Shen, Xiling
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
Germany: John Wiley & Sons, Inc
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More information
Scope and Contents
Contents
Colorectal cancer (CRC) metastasizes mainly to the liver, which accounts for the majority of CRC‐related deaths. Here it is shown that metastatic cells undergo specific chromatin remodeling in the liver. Hepatic growth factor (HGF) induces phosphorylation of PU.1, a pioneer factor, which in turn binds and opens chromatin regions of downstream effec...
Alternative Titles
Full title
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis
Authors, Artists and Contributors
Author / Creator
Wang, Ergang
Prado Balcazar, Jorge
Wu, Zhenzhen
Xiang, Kun
Wang, Yi
Huang, Qiang
Negrete, Marcos
Chen, Kai‐Yuan
Li, Wei
Fu, Yujie
Dohlman, Anders
Mines, Robert
Zhang, Liwen
Kobayashi, Yoshihiko
Chen, Tianyi
Shi, Guizhi
Shen, John Paul
Kopetz, Scott
Tata, Purushothama Rao
Moreno, Victor
Gersbach, Charles
Crawford, Gregory
Hsu, David
Huang, Emina
Bu, Pengcheng
Shen, Xiling
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d9e4ca4741b44963bbd7506d05a7e116
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d9e4ca4741b44963bbd7506d05a7e116
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202004673
