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Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifun...

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifun...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da9012e8705a4a99bac065cbb0ff65a7

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity

About this item

Full title

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2015-08, Vol.20 (8), p.14761-14776

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Six novel imidazoline derivatives were synthesized and tested in antifungal assays. One of the compounds, N-cyclohexyl-2-imino-3-(4-nitrophenyl)imidazolidine-1-carboxamide showed moderate activity against several clinical strains of Candida albicans. Its structure was solved by X-ray crystallography and its mode of action was deduced using molecula...

Alternative Titles

Full title

Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_da9012e8705a4a99bac065cbb0ff65a7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da9012e8705a4a99bac065cbb0ff65a7

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules200814761

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