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Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndr...

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db437a126ef0462aaf2bf7f51b8ed8e6

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

About this item

Full title

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

Publisher

Switzerland: MDPI AG

Journal title

Brain sciences, 2020-11, Vol.10 (12), p.899

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Glutamatergic receptor expression is mostly unknown in adults with fragile X syndrome (FXS). Favorable behavioral effects of negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR
) in
knockout (KO) mouse models have not been confirmed in humans with FXS. Measurement of cerebral mGluR
expression in hu...

Alternative Titles

Full title

Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_db437a126ef0462aaf2bf7f51b8ed8e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db437a126ef0462aaf2bf7f51b8ed8e6

Other Identifiers

ISSN

2076-3425

E-ISSN

2076-3425

DOI

10.3390/brainsci10120899

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