In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome enginee...
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering
About this item
Full title
Author / Creator
Wu, Qianxin , Ferry, Quentin R. V. , Baeumler, Toni A. , Michaels, Yale S. , Vitsios, Dimitrios M. , Habib, Omer , Arnold, Roland , Jiang, Xiaowei , Maio, Stefano , Steinkraus, Bruno R. , Tapia, Marta , Piazza, Paolo , Xu, Ni , Holländer, Georg A. , Milne, Thomas A. , Kim, Jin-Soo , Enright, Anton J. , Bassett, Andrew R. and Fulga, Tudor A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
RNA regulatory elements (RREs) are an important yet relatively under-explored facet of gene regulation. Deciphering the prevalence and functional impact of this post-transcriptional control layer requires technologies for disrupting RREs without perturbing cellular homeostasis. Here we describe genome-engineering based evaluation of RNA regulatory...
Alternative Titles
Full title
In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering
Authors, Artists and Contributors
Author / Creator
Ferry, Quentin R. V.
Baeumler, Toni A.
Michaels, Yale S.
Vitsios, Dimitrios M.
Habib, Omer
Arnold, Roland
Jiang, Xiaowei
Maio, Stefano
Steinkraus, Bruno R.
Tapia, Marta
Piazza, Paolo
Xu, Ni
Holländer, Georg A.
Milne, Thomas A.
Kim, Jin-Soo
Enright, Anton J.
Bassett, Andrew R.
Fulga, Tudor A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_db4eb21f42e2466d9fc7c9b4e4aa2f37
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db4eb21f42e2466d9fc7c9b4e4aa2f37
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00686-2
