Impact of APOE genotype on prion-type propagation of tauopathy
Impact of APOE genotype on prion-type propagation of tauopathy
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Apolipoprotein (APOE) is a major risk factor of Alzheimer’s disease (AD), with the E2, E3 and E4 isoforms differentially regulating the burden of AD-associated neuropathologies, such as amyloid β and tau. In AD, pathological tau is thought to spread along neuroanatomic connections following a prion-like mechanism. To provide insights into whether A...
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Full title
Impact of APOE genotype on prion-type propagation of tauopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_db66ca4de5b3405d8376205324775740
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db66ca4de5b3405d8376205324775740
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-022-01359-y
