High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals speci...
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
About this item
Full title
Author / Creator
Gomez-Cabrero, David , Almgren, Malin , Sjöholm, Louise K. , Hensvold, Aase H. , Ringh, Mikael V. , Tryggvadottir, Rakel , Kere, Juha , Scheynius, Annika , Acevedo, Nathalie , Reinius, Lovisa , Taub, Margaret A. , Montano, Carolina , Aryee, Martin J. , Feinberg, Jason I. , Feinberg, Andrew P. , Tegnér, Jesper , Klareskog, Lars , Catrina, Anca I. and Ekström, Tomas J.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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More information
Scope and Contents
Contents
Twin studies are powerful models to elucidate epigenetic modifications resulting from gene-environment interactions. Yet, commonly a limited number of clinical twin samples are available, leading to an underpowered situation afflicted with false positives and hampered by low sensitivity. We investigated genome-wide DNA methylation data from two sma...
Alternative Titles
Full title
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
Authors, Artists and Contributors
Author / Creator
Almgren, Malin
Sjöholm, Louise K.
Hensvold, Aase H.
Ringh, Mikael V.
Tryggvadottir, Rakel
Kere, Juha
Scheynius, Annika
Acevedo, Nathalie
Reinius, Lovisa
Taub, Margaret A.
Montano, Carolina
Aryee, Martin J.
Feinberg, Jason I.
Feinberg, Andrew P.
Tegnér, Jesper
Klareskog, Lars
Catrina, Anca I.
Ekström, Tomas J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dbc64c47c8d343fc8b18716a75f1c370
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dbc64c47c8d343fc8b18716a75f1c370
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-016-0374-0
