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ArticlesPeer ReviewedFull Text
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Author / Creator:McDonald, Oliver G ; Li, Xin ; Saunders, Tyler ; Tryggvadottir, Rakel ; Mentch, Samantha J ; Warmoes, Marc O ; Word, Anna E ; Carrer, Alessandro ; Salz, Tal H ; Natsume, Sonoko ; Stauffer, Kimberly M ; Makohon-Moore, Alvin ; Zhong, Yi ; Wu, Hao ; Wellen, Kathryn E ; Locasale, Jason W ; Iacobuzio-Donahue, Christine A ; Feinberg, Andrew P
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2017-03, Vol.49 (3), p.367-376
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ArticlesPeer ReviewedFull Text
DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation
Author / Creator:Lo, Emily K.W. ; Idrizi, Adrian ; Tryggvadottir, Rakel ; Zhou, Weiqiang ; Hou, Wenpin ; Ji, Hongkai ; Cahan, Patrick ; Feinberg, Andrew P.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2025-03, Vol.17 (1), p.32-19, Article 32
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ArticlesPeer ReviewedFull Text
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation
Author / Creator:Wulfridge, Phillip ; Davidovich, Adam ; Salvador, Anna C. ; Manno, Gabrielle C. ; Tryggvadottir, Rakel ; Idrizi, Adrian ; Huda, M. Nazmul ; Bennett, Brian J. ; Adams, L. Garry ; Hansen, Kasper D. ; Threadgill, David W. ; Feinberg, Andrew P.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2023-10, Vol.19 (10), p.e1010997-e1010997
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ArticlesPeer ReviewedFull Text
Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis
Author / Creator:Koldobskiy, Michael A. ; Jenkinson, Garrett ; Abante, Jordi ; Rodriguez DiBlasi, Varenka A. ; Zhou, Weiqiang ; Pujadas, Elisabet ; Idrizi, Adrian ; Tryggvadottir, Rakel ; Callahan, Colin ; Bonifant, Challice L. ; Rabin, Karen R. ; Brown, Patrick A. ; Ji, Hongkai ; Goutsias, John ; Feinberg, Andrew P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature biomedical engineering, 2021-04, Vol.5 (4), p.360-376
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ArticlesPeer ReviewedFull Text
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
Author / Creator:Gomez-Cabrero, David ; Almgren, Malin ; Sjöholm, Louise K. ; Hensvold, Aase H. ; Ringh, Mikael V. ; Tryggvadottir, Rakel ; Kere, Juha ; Scheynius, Annika ; Acevedo, Nathalie ; Reinius, Lovisa ; Taub, Margaret A. ; Montano, Carolina ; Aryee, Martin J. ; Feinberg, Jason I. ; Feinberg, Andrew P. ; Tegnér, Jesper ; Klareskog, Lars ; Catrina, Anca I. ; Ekström, Tomas J.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2016-11, Vol.8 (1), p.124-124, Article 124
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ArticlesPeer ReviewedFull Text
Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability
Author / Creator:Rizzardi, Lindsay F. ; Hickey, Peter F. ; Rodriguez DiBlasi, Varenka ; Tryggvadóttir, Rakel ; Callahan, Colin M. ; Idrizi, Adrian ; Hansen, Kasper D. ; Feinberg, Andrew P.
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-02, Vol.22 (2), p.307-316
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ArticlesPeer ReviewedFull Text
Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits
Author / Creator:Rizzardi, Lindsay F. ; Hickey, Peter F. ; Idrizi, Adrian ; Tryggvadóttir, Rakel ; Callahan, Colin M. ; Stephens, Kimberly E. ; Taverna, Sean D. ; Zhang, Hao ; Ramazanoglu, Sinan ; Hansen, Kasper D. ; Feinberg, Andrew P.
Publisher:England: BioMed Central
Journal title:Genome Biology, 2021-04, Vol.22 (1), p.116-116, Article 116
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ArticlesPeer ReviewedFull Text
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Author / Creator:Garrett-Bakelman, Francine E ; Darshi, Manjula ; Green, Stefan J ; Gur, Ruben C ; Lin, Ling ; Macias, Brandon R ; McKenna, Miles J ; Meydan, Cem ; Mishra, Tejaswini ; Nasrini, Jad ; Piening, Brian D ; Rizzardi, Lindsay F ; Sharma, Kumar ; Siamwala, Jamila H ; Taylor, Lynn ; Vitaterna, Martha Hotz ; Afkarian, Maryam ; Afshinnekoo, Ebrahim ; Ahadi, Sara ; Ambati, Aditya ; Arya, Maneesh ; Bezdan, Daniela ; Callahan, Colin M ; Chen, Songjie ; Choi, Augustine M K ; Chlipala, George E ; Contrepois, Kévin ; Covington, Marisa ; Crucian, Brian E ; De Vivo, Immaculata ; Dinges, David F ; Ebert, Douglas J ; Feinberg, Jason I ; Gandara, Jorge A ; George, Kerry A ; Goutsias, John ; Grills, George S ; Hargens, Alan R ; Heer, Martina ; Hillary, Ryan P ; Hoofnagle, Andrew N ; Hook, Vivian Y H ; Jenkinson, Garrett ; Jiang, Peng ; Keshavarzian, Ali ; Laurie, Steven S ; Lee-McMullen, Brittany ; Lumpkins, Sarah B ; MacKay, Matthew ; Maienschein-Cline, Mark G ; Melnick, Ari M ; Moore, Tyler M ; Nakahira, Kiichi ; Patel, Hemal H ; Pietrzyk, Robert ; Rao, Varsha ; Saito, Rintaro ; Salins, Denis N ; Schilling, Jan M ; Sears, Dorothy D ; Sheridan, Caroline K ; Stenger, Michael B ; Tryggvadottir, Rakel ; Urban, Alexander E ; Vaisar, Tomas ; Van Espen, Benjamin ; Zhang, Jing ; Ziegler, Michael G ; Zwart, Sara R ; Charles, John B ; Kundrot, Craig E ; Scott, Graham B I ; Bailey, Susan M ; Basner, Mathias ; Feinberg, Andrew P ; Lee, Stuart M C ; Mason, Christopher E ; Mignot, Emmanuel ; Rana, Brinda K ; Smith, Scott M ; Snyder, Michael P ; Turek, Fred W
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6436)
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ArticlesFull Text
Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology
Author / Creator:Ladd-Acosta, Christine ; Andrews, Shan V ; Bakulski, Kelly M ; Feinberg, Jason I ; Rakel Tryggvadottir ; Yao, Ruofan ; Croen, Lisa A ; Hertz-Picciotto, Irva ; Newschaffer, Craig J ; Salafia, Carolyn M ; Feinberg, Andrew P ; Hansen, Kasper D ; M Daniele Fallin
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-03
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ArticlesPeer ReviewedFull Text
Large-scale epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Author / Creator:McDonald, Oliver G. ; Li, Xin ; Saunders, Tyler ; Tryggvadottir, Rakel ; Mentch, Samantha J. ; Warmoes, Marc O. ; Word, Anna E. ; Carrer, Alessandro ; Salz, Tal H. ; Natsume, Sonoko ; Stauffer, Kimberly M. ; Makohon-Moore, Alvin ; Zhong, Yi ; Wu, Hao ; Wellen, Kathryn E. ; Locasale, Jason W. ; Iacobuzio-Donahue, Christine ; Feinberg, Andrew P.
Journal title:Nature genetics, 2017-01, Vol.49 (3), p.367-376
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ArticlesPeer ReviewedFull Text
An information-theory analysis of DNA methylation identifies converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia
Author / Creator:Koldobskiy, Michael A. ; Jenkinson, Garrett ; Abante, Jordi ; DiBlasi, Varenka A. Rodriguez ; Zhou, Weiqiang ; Pujadas, Elisabet ; Idrizi, Adrian ; Tryggvadottir, Rakel ; Callahan, Colin ; Bonifant, Challice L. ; Rabin, Karen R. ; Brown, Patrick A. ; Ji, Hongkai ; Goutsias, John ; Feinberg, Andrew P.
Journal title:Nature biomedical engineering, 2021-04, Vol.5 (4), p.360-376
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ArticlesFull Text
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric disease heritability
Author / Creator:Rizzardi, Lindsay ; Hickey, Peter ; Rodriguez, Varenka ; Rakel Tryggvadottir ; Callahan, Colin ; Idrizi, Adrian ; Hansen, Kasper ; Feinberg, Andrew P
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2017-03
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ArticlesFull Text
Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traits
Author / Creator:Rizzardi, Lindsay F ; Hickey, Peter F ; Idrizi, Adrian ; Rakel Tryggvadóttir ; Callahan, Colin M ; Stephens, Kimberly E ; Taverna, Sean D ; Zhang, Hao ; Ramazanoglu, Sinan ; Consortium, Gtex ; Hansen, Kasper D ; Feinberg, Andrew P
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-01
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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

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DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation

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Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

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Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis

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High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

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Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

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Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits

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The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

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Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology

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Large-scale epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

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An information-theory analysis of DNA methylation identifies converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia

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Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric disease heritability

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Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traits

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