Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled c...
Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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The epithelial anion transporter SLC26A9 contributes to airway surface hydration and gastric acid production. Colocalizing with CFTR, SLC26A9 has been proposed as a target for the treatment of cystic fibrosis. To provide molecular details of its transport mechanism, we present cryo-EM structures and a functional characterization of murine Slc26a9....
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Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport
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TN_cdi_doaj_primary_oai_doaj_org_article_dbe2fb604f9d45c8a7fe11a823aff74f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dbe2fb604f9d45c8a7fe11a823aff74f
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.46986
