Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therape...
Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Highly concentrated antibody formulations are oftentimes required for subcutaneous, self-administered biologics. Here, we report the development of a unique formulation for our first-in-class FSH-blocking humanized antibody, MS-Hu6, which we propose to move to the clinic for osteoporosis, obesity, and Alzheimer's disease. The studies were carried o...
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Full title
Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration
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TN_cdi_doaj_primary_oai_doaj_org_article_dbfcd21d71574f6ca1d659719f942a73
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dbfcd21d71574f6ca1d659719f942a73
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.88898
