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Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ patholo...

Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ patholo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc5e597fa919457eaabb9d675def2f90

Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology

About this item

Full title

Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology

Publisher

England: BioMed Central

Journal title

Biological research, 2024-08, Vol.57 (1), p.56-16, Article 56

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Synaptic dysfunction is an early feature in Alzheimer's disease (AD) pathogenesis and a major morphological correlate of memory deficits. Given the main synaptic location of N-methyl-D-aspartate receptors (NMDARs), their dysregulation has been implicated in these pathological effects. Here, to detect possible alterations in the expression and synap...

Alternative Titles

Full title

Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dc5e597fa919457eaabb9d675def2f90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc5e597fa919457eaabb9d675def2f90

Other Identifiers

ISSN

0717-6287,0716-9760

E-ISSN

0717-6287

DOI

10.1186/s40659-024-00537-7

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