Translational error in mice increases with ageing in an organ-dependent manner
Translational error in mice increases with ageing in an organ-dependent manner
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The accuracy of protein synthesis and its relation to ageing has been of long-standing interest. To study whether spontaneous changes in the rate of ribosomal error occur as a function of age, we first determined that stop-codon readthrough is a more sensitive read-out of mistranslation due to codon-anticodon mispairing than missense amino acid inc...
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Translational error in mice increases with ageing in an organ-dependent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_dc79bb1a66334ff68c3c1cc102b48ef8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc79bb1a66334ff68c3c1cc102b48ef8
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2041-1723
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2041-1723
DOI
10.1038/s41467-025-57203-z