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Translational error in mice increases with ageing in an organ-dependent manner

Translational error in mice increases with ageing in an organ-dependent manner

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc79bb1a66334ff68c3c1cc102b48ef8

Translational error in mice increases with ageing in an organ-dependent manner

About this item

Full title

Translational error in mice increases with ageing in an organ-dependent manner

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-02, Vol.16 (1), p.2069-13

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The accuracy of protein synthesis and its relation to ageing has been of long-standing interest. To study whether spontaneous changes in the rate of ribosomal error occur as a function of age, we first determined that stop-codon readthrough is a more sensitive read-out of mistranslation due to codon-anticodon mispairing than missense amino acid inc...

Alternative Titles

Full title

Translational error in mice increases with ageing in an organ-dependent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dc79bb1a66334ff68c3c1cc102b48ef8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc79bb1a66334ff68c3c1cc102b48ef8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-57203-z

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