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Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription...

Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc813a76f1a44fa790c36e641522a47c

Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning

About this item

Full title

Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-03, Vol.9 (1), p.899-16, Article 899

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Oligodendrocytes produce myelin for rapid transmission and saltatory conduction of action potentials in the vertebrate central nervous system. Activation of the myelination program requires several transcription factors including Sox10, Olig2, and Nkx2.2. Functional interactions among them are poorly understood and important components of the regul...

Alternative Titles

Full title

Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dc813a76f1a44fa790c36e641522a47c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc813a76f1a44fa790c36e641522a47c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03336-3

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