Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Chall...
Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection
About this item
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Author / Creator
Clever, Sabrina , Limpinsel, Leonard , Meyer Zu Natrup, Christian , Schünemann, Lisa-Marie , Beythien, Georg , Rosiak, Malgorzata , Hülskötter, Kirsten , Gregor, Katharina Manuela , Tuchel, Tamara , Kalodimou, Georgia , Freudenstein, Astrid , Kumar, Satendra , Baumgärtner, Wolfgang , Sutter, Gerd , Tscherne, Alina and Volz, Asisa
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
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Scope and Contents
Contents
The sudden emergence of SARS-CoV-2 demonstrates the need for new vaccines that rapidly protect in the case of an emergency. In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SARS-CoV-2 nucleoprotein (N, MVA-SARS-2-ST/N) as an approach to further improve vaccine-induced immunog...
Alternative Titles
Full title
Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dce965dac07f41e881175ae99326794b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dce965dac07f41e881175ae99326794b
Other Identifiers
ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v16030417
