Serotonergic system in vivo with [11C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive...
Serotonergic system in vivo with [11C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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GTP-cyclohydrolase deficiency in dopa-responsive dystonia (DRD) patients impairs the biosynthesis of dopamine, but also of serotonin. The high prevalence of non-motor symptoms suggests involvement of the serotonergic pathway. Our study aimed to investigate the serotonergic system in vivo in the brain of`DRD patients and correlate this to (non-)moto...
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Serotonergic system in vivo with [11C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
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TN_cdi_doaj_primary_oai_doaj_org_article_dd3b0bff2a6c4eb5a4997a0bcdc1eef6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd3b0bff2a6c4eb5a4997a0bcdc1eef6
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2045-2322
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2045-2322
DOI
10.1038/s41598-022-10067-5