The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The SARS-CoV-2 nucleocapsid (N) protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that underlie this process are poorly understood. Here we combine single-molecule spectroscopy with all-atom simulations to uncover the molecular details that contribute to N protein function. N protein contains...
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Full title
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
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TN_cdi_doaj_primary_oai_doaj_org_article_dd6a306bbe1846f28cbf4f152c659197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd6a306bbe1846f28cbf4f152c659197
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21953-3
