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MAP3K1 regulates female reproductive tract development

MAP3K1 regulates female reproductive tract development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd7b0bd517df4bf9b9bf58ec980d661c

MAP3K1 regulates female reproductive tract development

About this item

Full title

MAP3K1 regulates female reproductive tract development

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2024-03, Vol.17 (3)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Mitogen-activated protein 3 kinase 1 (MAP3K1) has a plethora of cell type-specific functions not yet fully understood. Herein, we describe a role for MAP3K1 in female reproductive tract (FRT) development. MAP3K1 kinase domain-deficient female mice exhibited an imperforate vagina, labor failure and infertility. These defects corresponded with shunte...

Alternative Titles

Full title

MAP3K1 regulates female reproductive tract development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dd7b0bd517df4bf9b9bf58ec980d661c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd7b0bd517df4bf9b9bf58ec980d661c

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.050669

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