Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids
Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Patient-derived tumor organoids (PDOs) are a highly promising preclinical model that recapitulates the histology, gene expression, and drug response of the donor patient tumor. Currently, PDO culture relies on basement-membrane extract (BME), which suffers from batch-to-batch variability, the presence of xenogeneic compounds and residual growth fac...
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Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids
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TN_cdi_doaj_primary_oai_doaj_org_article_dda5710243f944a48c6092025f6d253a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dda5710243f944a48c6092025f6d253a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28788-6
