HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of...
HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1/2 pathway
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Pyroptosis is a form of proinflammatory gasdermin-mediated programmed cell death. Abnormal mucosal inflammation in the intestine is a critical risk factor for colitis-associated colorectal cancer (CAC). However, it is unknown whether pyroptosis participates in the development of CAC.
To investigate the role of gasdermin E (GSDME)-mediated pyropt...
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Full title
HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1/2 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_ddb21ec6035c4a0a8e051c18fba713e9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ddb21ec6035c4a0a8e051c18fba713e9
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-020-00985-0
